Heleen M Wortelboer: search on Z-Library

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1

A Proof-of-Concept System Dynamics Simulation Model of the Development of Burnout and Recovery Using Retrospective Case Data

Veldhuis, Guido A., Sluijs, Teun, van Zwieten, Marianne H. J., Bouwman, Jildau, Wiezer, Noortje M., Wortelboer, Heleen M.

Journal:

International Journal of Environmental Research and Public Health

Year:

2020

File:

PDF, 4.50 MB

2020

2

Grip on health: A complex systems approach to transform health care

van Wietmarschen, Herman A., Wortelboer, Heleen M., van der Greef, Jan

Journal:

Journal of Evaluation in Clinical Practice

Year:

2016

Language:

english

File:

PDF, 459 KB

english, 2016

3

Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2

Jelmer J. van Zanden, Heleen M. Wortelboer, Sabina Bijlsma, Ans Punt, Mustafa Usta, Peter J. van Bladeren, Ivonne M.C.M. Rietjens, Nicole H.P. Cnubben

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 360 KB

english, 2005

4

The interplay of glutathione-related processes in antioxidant defense

Nicole H.P Cnubben, Ivonne M.C.M Rietjens, Heleen Wortelboer, Jelmer van Zanden, Peter J van Bladeren

Journal:

Environmental Toxicology and Pharmacology

Year:

2001

Language:

english

File:

PDF, 333 KB

english, 2001

5

Protein transport across the small intestine in food allergy

Reitsma, Marit, Westerhout, Joost, Wichers, Harry J., Wortelboer, Heleen M., Verhoeckx, Kitty C. M.

Journal:

Molecular Nutrition & Food Research

Year:

2014

Language:

english

File:

PDF, 689 KB

english, 2014

6

Nutrient-induced glucagon like peptide-1 release is modulated by serotonin

Ripken, Dina, van der Wielen, Nikkie, Wortelboer, Heleen M., Meijerink, Jocelijn, Witkamp, Renger F., Hendriks, Henk F.J.

Journal:

The Journal of Nutritional Biochemistry

Year:

2016

Language:

english

File:

PDF, 887 KB

english, 2016

7

Fish oil and inflammatory status alter the n-3 to n-6 balance of the endocannabinoid and oxylipin metabolomes in mouse plasma and tissues

Balvers, Michiel G. J., Verhoeckx, Kitty C. M., Bijlsma, Sabina, Rubingh, Carina M., Meijerink, Jocelijn, Wortelboer, Heleen M., Witkamp, Renger F.

Journal:

Year:

2012

Language:

english

File:

PDF, 450 KB

english, 2012

8

Metabolism of ATP-binding cassette drug transporter inhibitors: complicating factor for multidrug resistance

Cnubben, Nicole HP, Wortelboer, Heleen M, van Zanden, Jelmer J, Rietjens, Ivonne MCM, van Bladeren, Peter J

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2005

Language:

english

File:

PDF, 283 KB

english, 2005

9

Liquid chromatography–tandem mass spectrometry analysis of free and esterified fatty acid N-acyl ethanolamines in plasma and blood cells

Balvers, Michiel G.J., Wortelboer, Heleen M., Witkamp, Renger F., Verhoeckx, Kitty C.M.

Journal:

Analytical Biochemistry

Year:

2013

Language:

english

File:

PDF, 546 KB

english, 2013

10

Differences in the effects of model inducers of cytochrome P450 on the biotransformation of scoparone in rat and hamster liver

Wim C. Mennes, Niels B. Lucas Luijckx, Heleen M. Wortelboer, Jan Noordhoek, Bas J. Blaauboer

Journal:

Archives of Toxicology

Year:

1993

Language:

english

File:

PDF, 619 KB

english, 1993

11

Presence, formation and putative biological activities of N-acyl serotonins, a novel class of fatty-acid derived mediators, in the intestinal tract

Kitty C.M. Verhoeckx, Trudy Voortman, Michiel G.J. Balvers, Henk F.J. Hendriks, Heleen M.Wortelboer, Renger F. Witkamp

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2011

Language:

english

File:

PDF, 634 KB

english, 2011

12

Predicting carrier-mediated hepatic disposition of rosuvastatin in man by scaling from individual transfected cell-lines in vitro using absolute transporter protein quantification and PBPK modeling

Bosgra, Sieto, van de Steeg, Evita, Vlaming, Maria L., Verhoeckx, Kitty C., Huisman, Maarten T., Verwei, Miriam, Wortelboer, Heleen M.

Journal:

European Journal of Pharmaceutical Sciences

Year:

2014

Language:

english

File:

PDF, 984 KB

english, 2014

13

Glutathione-dependent interaction of heavy metal compounds with multidrug resistance proteins MRP1 and MRP2

Heleen M. Wortelboer, Michiel G.J. Balvers, Mustafa Usta, Peter J. van Bladeren, Nicole H.P. Cnubben

Journal:

Environmental Toxicology and Pharmacology

Year:

2008

Language:

english

File:

PDF, 405 KB

english, 2008

14

Antioxidant status of Fanconi anemia fibroblasts

Johan J. P. Gille, Heleen M. Wortelboer, Hans Joenje

Journal:

Year:

1987

Language:

english

File:

PDF, 474 KB

english, 1987

15

Short-term fatty acid intervention elicits differential gene expression responses in adipose tissue from lean and overweight men

Marjan J. van Erk, Wilrike J. Pasman, Heleen M. Wortelboer, Ben van Ommen, Henk F. J. Hendriks

Journal:

Genes & Nutrition

Year:

2008

Language:

english

File:

PDF, 532 KB

english, 2008

16

Effect of body fat distribution on the transcription response to dietary fat interventions

Marijana Radonjic, Marjan J. van Erk, Wilrike J. Pasman, Heleen M. Wortelboer, Henk F. J. Hendriks, Ben van Ommen

Journal:

Genes & Nutrition

Year:

2009

Language:

english

File:

PDF, 378 KB

english, 2009

17

Inhibition of multidrug resistance proteins MRP1 and MRP2 by a series of α,β-unsaturated carbonyl compounds

Heleen M. Wortelboer, Mustafa Usta, Jelmer J. van Zanden, Peter J. van Bladeren, Ivonne M.C.M. Rietjens, Nicole H.P. Cnubben

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 456 KB

english, 2005

18

HEPATIC TRANSPORTER PROTEIN EXPRESSION IN FETUSES, NEONATES AND YOUNG INFANTS

Mooij, Miriam, de Steeg, Evita Van, Wortelboer, Heleen, Vaes, Wouter, Tibboel, Dick, Wildt, Saskia De

Journal:

Archives of Disease in Childhood

Year:

2016

Language:

english

File:

PDF, 57 KB

english, 2016

19

Docosahexaenoic acid and eicosapentaenoic acid are converted by 3T3-L1 adipocytes to N-acyl ethanolamines with anti-inflammatory properties

Michiel G.J. Balvers, Kitty C.M. Verhoeckx, Pierluigi Plastina, Heleen M. Wortelboer, Jocelijn Meijerink, Renger F. Witkamp

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2010

Language:

english

File:

PDF, 906 KB

english, 2010

20

Time-dependent effect of in vivo inflammation on eicosanoid and endocannabinoid levels in plasma, liver, ileum and adipose tissue in C57BL/6 mice fed a fish-oil diet

Michiel G.J. Balvers, Kitty C.M. Verhoeckx, Jocelijn Meijerink, Sabina Bijlsma, Carina M. Rubingh, Heleen M. Wortelboer, Renger F. Witkamp

Journal:

International Immunopharmacology

Year:

2012

Language:

english

File:

PDF, 686 KB

english, 2012

21

Ex vivo systems to study host–microbiota interactions in the gastrointestinal tract

Roeselers, Guus, Ponomarenko, Michael, Lukovac, Sabina, Wortelboer, Heleen M.

Journal:

Best Practice & Research Clinical Gastroenterology

Year:

2013

Language:

english

File:

PDF, 885 KB

english, 2013

22

Interaction of Digitalis-Like Compounds with Liver Uptake Transporters NTCP, OATP1B1, and OATP1B3

Gozalpour, Elnaz, Greupink, Rick, Wortelboer, Heleen M., Bilos, Albert, Schreurs, Marieke, Russel, Frans G. M., Koenderink, Jan B.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.51 MB

english, 2014

23

A higher throughput and physiologically relevant two-compartmental human ex vivo intestinal tissue system for studying gastrointestinal processes

Stevens, Lianne J., van Lipzig, Marola M.H., Erpelinck, Steven L.A., Pronk, A., van Gorp, J., Wortelboer, Heleen M., van de Steeg, Evita

Journal:

European Journal of Pharmaceutical Sciences

Year:

2019

Language:

english

File:

PDF, 1.05 MB

english, 2019

24

Interaction of immunosuppressive drugs with human organic anion transporter (OAT) 1 and OAT3, and multidrug resistance-associated protein (MRP) 2 and MRP4

El-Sheikh, Azza A.K., Greupink, Rick, Wortelboer, Heleen M., van den Heuvel, Jeroen J.M.W., Schreurs, Marieke, Koenderink, Jan B., Masereeuw, Rosalinde, Russel, Frans G.M.

Journal:

Translational Research

Year:

2013

Language:

english

File:

PDF, 1.07 MB

english, 2013

25

Measurement of Palmitoylethanolamide and Other N-Acylethanolamines During Physiological and Pathological Conditions

G.J. Balvers, Michiel, C.M. Verhoeckx, Kitty, Meijerink, Jocelijn, M. Wortelboer, Heleen, F. Witkamp, Renger

Journal:

CNS & Neurological Disorders - Drug Targets (Formerly Current Drug Targets - CNS & Neurological Disorders)

Year:

2013

File:

PDF, 732 KB

2013

26

Glutathione-dependent transport of heavy metal compounds by multidrug resistance proteins MRP1 and MRP2

Nicole H.P. Cnubben, Michiel G.J. Balvers, Mustafa Usta, Jelmer J. van Zanden, Peter J. van Bladeren, Ivonne M.C.M. Rietjens, Heleen M. Wortelboer

Journal:

Toxicology Letters

Year:

2006

Language:

english

File:

PDF, 85 KB

english, 2006

27

Proteomics of human liver membrane transporters: A focus on fetuses and newborn infants

van Groen, Bianca D., van de Steeg, Evita, Mooij, Miriam G., van Lipzig, Marola M.H., de Koning, Barbara A.E., Verdijk, Robert M., Wortelboer, Heleen M., Gaedigk, Roger, Bi, Chengpeng, Steven Leeder,

Journal:

European Journal of Pharmaceutical Sciences

Year:

2018

Language:

english

File:

PDF, 2.74 MB

english, 2018

28

Impact of maternal diets and early environmental exposure on weight maintenance and development of the offspring

André Wolterbeek, Simone Eussen, Renate Jansink, Linda van de Horst, Marlies Otto, Ine Waalkens, Berensen Anja Dijkstra, Florence Salmon, Heleen Wortelboer, Wilrike Pasman, Henk Hendriks, Ivana Bobeld

Journal:

Toxicology Letters

Year:

2006

Language:

english

File:

PDF, 100 KB

english, 2006

29

Development of an in vitro stem cell assay to test developmental neurotoxicity

Didima De Groot, Hanneke Stegeman, Akash Bhola, Jan Lammers, Andre Wolterbeek, Heleen Wortelboer, Remco Westerink, Andrea Seiler, Johan Van Burgsteden

Journal:

Toxicology Letters

Year:

2008

Language:

english

File:

PDF, 95 KB

english, 2008

30

Human Glutathione S-Transferase-Mediated Glutathione Conjugation of Curcumin and Efflux of These Conjugates in Caco-2 Cells

Usta, Mustafa, Wortelboer, Heleen M., Vervoort, Jacques, Boersma, Marelle G., Rietjens, Ivonne M. C. M., van Bladeren, Peter J., Cnubben, Nicole H. P.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 143 KB

english, 2007

31

Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells

Jelmer J van Zanden, Liesbeth Geraets, Heleen M Wortelboer, Peter J.van Bladeren, Ivonne M.C.M Rietjens, Nicole H.P Cnubben

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 237 KB

english, 2004

32

Increasing oxime efficacy by blood–brain barrier modulation

Marloes J.A. Joosen, Marcel J. van der Schans, Christian G.M. van Dijk, Willem C. Kuijpers, Heleen M. Wortelboer, Herman P.M. van Helden

Journal:

Toxicology Letters

Year:

2011

Language:

english

File:

PDF, 404 KB

english, 2011

33

Steviol Glycoside Rebaudioside A Induces Glucagon-like Peptide-1 and Peptide YY Release in a Porcine ex Vivo Intestinal Model

Ripken, Dina, van der Wielen, Nikkie, Wortelboer, Heleen M., Meijerink, Jocelijn, Witkamp, Renger F., Hendriks, Henk F. J.

Journal:

Journal of Agricultural and Food Chemistry

Year:

2014

Language:

english

File:

PDF, 267 KB

english, 2014

34

Regional Expression Levels of Drug Transporters and Metabolizing Enzymes along the Pig and Human Intestinal Tract and Comparison with Caco-2 Cells

Vaessen, Stefan F.C., van Lipzig, Marola M.H., Pieters, Raymond H.H., Krul, Cyrille A.M., Wortelboer, Heleen M., van de Steeg, Evita

Journal:

Drug Metabolism and Disposition

Year:

2017

Language:

english

File:

PDF, 837 KB

english, 2017

35

Reversal of in vitro cellular MRP1 and MRP2 mediated vincristine resistance by the flavonoid myricetin

Jelmer J. van Zanden, Anika de Mul, Heleen M. Wortelboer, Mustafa Usta, Peter J. van Bladeren, Ivonne M.C.M. Rietjens, Nicole H.P. Cnubben

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 260 KB

english, 2005

36

Effects of Long- and Short-Chain Fatty Acids on the Release of Gastrointestinal Hormones using an ex Vivo Porcine Intestinal Tissue Model

Voortman, Trudy, Hendriks, Henk F. J., Witkamp, Renger F., Wortelboer, Heleen M.

Journal:

Journal of Agricultural and Food Chemistry

Year:

2012

Language:

english

File:

PDF, 556 KB

english, 2012

37

The effect of quercetin phase II metabolism on its MRP1 and MRP2 inhibiting potential

Jelmer J. van Zanden, Hester van der Woude, Judith Vaessen, Mustafa Usta, Heleen M. Wortelboer, Nicole H.P. Cnubben, Ivonne M.C.M. Rietjens

Journal:

Biochemical Pharmacology

Year:

2007

Language:

english

File:

PDF, 337 KB

english, 2007

38

Maternal diets and early environmental exposure influences weight maintenance and development of the offspring

André Wolterbeek, Simone Eussen, Renate Jansink, Linda van der Horst, Marlies Otto, Ine Waalkens, Anja Dijkstra, Florence Salmon, Heleen Wortelboer, Wilrike Pasman, Henk Hendriks, Ivana Bobeldijk, Did

Journal:

Toxicology Letters

Year:

2007

Language:

english

File:

PDF, 75 KB

english, 2007

39

Interplay between MRP Inhibition and Metabolism of MRP Inhibitors: The Case of Curcumin

Wortelboer, Heleen M., Usta, Mustafa, van der Velde, Astrid E., Boersma, Marelle G., Spenkelink, Bert, van Zanden, Jelmer J., Rietjens, Ivonne M. C. M., van Bladeren, Peter J., Cnubben, Nicole H. P.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 159 KB

english, 2003

40

A new approach to predict human intestinal absorption using porcine intestinal tissue and biorelevant matrices

Westerhout, Joost, Steeg, Evita van de, Grossouw, Dimitri, Zeijdner, Evelijn E., Krul, Cyrille A.M., Verwei, Miriam, Wortelboer, Heleen M.

Journal:

European Journal of Pharmaceutical Sciences

Year:

2014

Language:

english

File:

PDF, 783 KB

english, 2014

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